منابع مشابه
Genetic Variation of Choline Dehydrogenase Gene in Idiopathic Male Infertility
Infertility can be caused by an unexplained reduction in semen quality in males who present asnormal on physical examination and endocrine testing. There is some evidence that aberrantmetabolism of micronutrients such as choline may play a causative role in male factorinfertility. Choline is a crucial factor in the regulation of sperm membrane structure andmotility, and this nutrient plays an i...
متن کاملStudies on choline dehydrogenase. II. Components of the choline oxidase system and the site of action of amytal.
Rat liver choline dehydrogenase has been known for many years to be one of the “cytochrome-reducing dehydrogenases” (1). Although it is functionally and structurally linked to the respiratory chain and acts without the mediation of readily dissociable coenzymes (2)) the cytochrome components linking choline dehydrogenase to oxygen have not been established. The purpose of this investigation was...
متن کاملStudies on Choline Dehydrogenase* II. COMPONENTS OF THE CHOLINE OXIDASE SYSTEM AND THE SITE OF ACTION OF AMYTAL
Rat liver choline dehydrogenase has been known for many years to be one of the “cytochrome-reducing dehydrogenases” (1). Although it is functionally and structurally linked to the respiratory chain and acts without the mediation of readily dissociable coenzymes (2)) the cytochrome components linking choline dehydrogenase to oxygen have not been established. The purpose of this investigation was...
متن کاملStudies on choline dehydrogenase. I. Extraction in soluble form, assay, and some properties of the enzyme.
The majority of the dehydrogenases of mammalian mitochondria are linked to the respiratory chain (cytochrome system) by way of pyridine nucleotides. Although the intramitochondrial pyridine nucleotide appears to be tightly bound in intact mitochondrial preparations (1) and thus does not function as a mobile coenzyme, the requirement of these dehydrogenases for added diphosphopyridine nucleotide...
متن کاملStudies on Succinic Dehydrogenase
About 2 years ago the author reported that the activity of purified preparations of succinic dehydrogenase is enhanced by phosphate buffer (2). This enhancement was dependent upon the phosphate concentration and appeared to be relatively specific for phosphate, since other buffers, such as Tris,l imidazole, histidine, glycylglycine, and arsenate did not induce it (2, 3). Arsenate, in fact, inte...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1959
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)70058-6